Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation Book Reviews
Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation by Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman Book Summary
In sexually reproducing organisms, embryos specify germ cells, which ultimately generate sperm and eggs. In Caenorhabditis elegans, the first germ cell is established when RNA and protein-rich P granules localize to the posterior of the one-cell embryo. Localization of P granules and their physical nature remain poorly understood. Here we show that P granules exhibit liquid-like behaviors, including fusion, dripping, and wetting, which we used to estimate their viscosity and surface tension. As with other liquids, P granules rapidly dissolved and condensed. Localization occurred by a biased increase in P granule condensation at the posterior. This process reflects a classic phase transition, in which polarity proteins vary the condensation point across the cell. Such phase transitions may represent a fundamental physicochemical mechanism for structuring
the cytoplasm.
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| Book Name | Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation |
| Genre | Biology |
| Author | Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman |
| Published | 21 May 2009, Thursday |
| Language | English |
| E-Book Size | 60.5 MB |
Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation (Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman) Book Reviews 2024
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Summary of Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation by Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman
The Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation book written by Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman was published on 21 May 2009, Thursday in the Biology category. A total of 76 readers of the book gave the book 0 points out of 5.
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Clifford P. Branwynne, Christian R. Eckmann, David S. Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher & Anthony A. Hyman - Germline P Granules are Liquid Droplets that Localize by Cotrolled Dissolution / Condensation Discussions & Comments
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