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The 2001 anthrax attacks, also known as Amerithrax (a combination of "America" and "anthrax", from its FBI case name), occurred in the United States over the course of several weeks beginning on September 18, 2001, one week after the September 11 terrorist attacks. Letters containing anthrax spores were mailed to several news media offices and to Senators Tom Daschle and Patrick Leahy, killing five people and infecting 17 others. Capitol Police Officers and staffers working for Senator Russ Feingold were exposed as well. According to the FBI, the ensuing investigation became "one of the largest and most complex in the history of law enforcement". A major focus in the early years of the investigation was bioweapons expert Steven Hatfill, who was eventually exonerated. Bruce Edwards Ivins, a scientist at the government's biodefense labs at Fort Detrick in Frederick, Maryland, became a focus around April 4, 2005. On April 11, 2007, Ivins was put under periodic surveillance and an FBI document stated that he was "an extremely sensitive suspect in the 2001 anthrax attacks". On July 29, 2008, Ivins committed suicide with an overdose of acetaminophen (Tylenol/Panadol). Federal prosecutors declared Ivins the sole perpetrator on August 6, 2008, based on DNA evidence leading to an anthrax vial in his lab. Two days later, Senator Chuck Grassley and Representative Rush D. Holt Jr. called for hearings into the Department of Justice and FBI's handling of the investigation. The FBI formally closed its investigation on February 19, 2010. In 2008, the FBI requested a review of the scientific methods used in their investigation from the National Academy of Sciences, which released their findings in the 2011 report Review of the Scientific Approaches Used During the FBI's Investigation of the 2001 Anthrax Letters. The report cast doubt on the government's conclusion that Ivins was the perpetrator, finding that the type of anthrax used in the letters was correctly identified as the Ames strain of the bacterium, but that there was insufficient scientific evidence for the FBI's assertion that it originated from Ivins' laboratory. The FBI responded by saying that the review panel asserted that it would not be possible to reach a definite conclusion based on science alone, and said that a combination of factors led the FBI to conclude that Ivins had been the perpetrator. Some information is still sealed concerning the case and Ivins' mental health.: 8 footnote  The government settled lawsuits that were filed by the widow of the first anthrax victim Bob Stevens for $2.5 million with no admission of liability. The settlement was reached solely for the purpose of "avoiding the expenses and risks of further litigations", according to a statement in the agreement. Context The anthrax attacks began just a week after the September 11 attacks, which had caused the destruction of the original World Trade Center in New York City, damage to the Pentagon in Arlington, Virginia, and the crash of an airliner in Shanksville, Pennsylvania. The attacks came in two waves. The first set of letters containing anthrax had a Trenton, New Jersey, postmark dated September 18, 2001. Five letters are believed to have been mailed at this time to ABC News, CBS News, NBC News and the New York Post, all located in New York City, and to the National Enquirer at American Media, Inc., (AMI) in Boca Raton, Florida. The first known victim of the attacks, Robert Stevens, who worked at the Sun tabloid, also published by AMI, died on October 5, 2001, four days after entering a Florida hospital with an undiagnosed illness that caused him to vomit and be short of breath. The presumed letter containing the anthrax which killed Stevens was never found. Only the New York Post and NBC News letters were actually identified; the existence of the other three letters is inferred because individuals at ABC, CBS and AMI became infected with anthrax. Scientists examining the anthrax from the New York Post letter said it was a clumped coarse brown granular material which looked similar to dog food. Two more anthrax letters, bearing the same Trenton postmark, were dated October 9, three weeks after the first mailing. The letters were addressed to two U.S. Senators, Tom Daschle of South Dakota and Patrick Leahy of Vermont. At the time, Daschle was the Senate majority leader and Leahy was head of the Senate Judiciary Committee; both were members of the Democratic Party. The Daschle letter was opened by an aide, Grant Leslie, on October 15, after which the government mail service was immediately shut down. The unopened Leahy letter was discovered in an impounded mailbag on November 16. The Leahy letter had been misdirected to the State Department mail annex in Sterling, Virginia, because a ZIP code was misread; a postal worker there, David Hose, contracted inhalational anthrax. More potent than the first anthrax letters, the material in the Senate letters was a highly refined dry powder consisting of about one gram of nearly pure spores. A series of conflicting news reports appeared, some claiming the powders had been "weaponized" with silica. Bioweapons experts who later viewed images of the anthrax used in the attacks saw no indication of "weaponization". Tests at Sandia National Laboratories in early 2002 confirmed that the attack powders were not weaponized. At least 22 people developed anthrax infections, 11 of whom contracted the especially life-threatening inhalational variety. Five died of inhalational anthrax: Stevens; two employees of the Brentwood mail facility in Washington, D.C. (Thomas Morris Jr. and Joseph Curseen), and two whose source of exposure to the bacteria is still unknown: Kathy Nguyen, a Vietnamese immigrant resident of the New York City borough of the Bronx who worked in the city, and the last known victim, Ottilie Lundgren, a 94-year-old widow of a prominent judge from Oxford, Connecticut. Because it took so long to identify a culprit, the 2001 anthrax attacks have been compared to the Unabomber attacks which took place from 1978 to 1995. Letters Authorities believe that the anthrax letters were mailed from Princeton, New Jersey. Investigators found anthrax spores in a city street mailbox located at 10 Nassau Street near the Princeton University campus. About 600 mailboxes were tested for anthrax which could have been used to mail the letters, and the Nassau Street box was the only one to test positive. The New York Post and NBC News letters contained the following note: The second note was addressed to Senators Daschle and Leahy and read: All of the letters were copies made by a copy machine, and the originals were never found. Each letter was trimmed to a slightly different size. The Senate letter uses punctuation, while the media letter does not. The handwriting on the media letter and envelopes is roughly twice the size of the handwriting on the Senate letter and envelopes. The envelopes addressed to .... Discover the Daniel Greenbrook popular books. Find the top 100 most popular Daniel Greenbrook books.