Tw Harris Popular Books

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Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs, the knee and hip joints, and the joints of the neck and lower back. The symptoms can interfere with work and normal daily activities. Unlike some other types of arthritis, only the joints, not internal organs, are affected.Causes include previous joint injury, abnormal joint or limb development, and inherited factors. Risk is greater in those who are overweight, have legs of different lengths, or have jobs that result in high levels of joint stress. Osteoarthritis is believed to be caused by mechanical stress on the joint and low grade inflammatory processes. It develops as cartilage is lost and the underlying bone becomes affected. As pain may make it difficult to exercise, muscle loss may occur. Diagnosis is typically based on signs and symptoms, with medical imaging and other tests used to support or rule out other problems. In contrast to rheumatoid arthritis, in osteoarthritis the joints do not become hot or red.Treatment includes exercise, decreasing joint stress such as by rest or use of a cane, support groups, and pain medications. Weight loss may help in those who are overweight. Pain medications may include paracetamol (acetaminophen) as well as NSAIDs such as naproxen or ibuprofen. Long-term opioid use is not recommended due to lack of information on benefits as well as risks of addiction and other side effects. Joint replacement surgery may be an option if there is ongoing disability despite other treatments. An artificial joint typically lasts 10 to 15 years.Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population, as of 2015. It becomes more common as people age. Among those over 60 years old, about 10% of males and 18% of females are affected. Osteoarthritis is the cause of about 2% of years lived with disability. Signs and symptoms The main symptom is pain, causing loss of ability and often stiffness. The pain is typically made worse by prolonged activity and relieved by rest. Stiffness is most common in the morning, and typically lasts less than thirty minutes after beginning daily activities, but may return after periods of inactivity. Osteoarthritis can cause a crackling noise (called "crepitus") when the affected joint is moved, especially shoulder and knee joint. A person may also complain of joint locking and joint instability. These symptoms would affect their daily activities due to pain and stiffness. Some people report increased pain associated with cold temperature, high humidity, or a drop in barometric pressure, but studies have had mixed results.Osteoarthritis commonly affects the hands, feet, spine, and the large weight-bearing joints, such as the hips and knees, although in theory, any joint in the body can be affected. As osteoarthritis progresses, movement patterns (such as gait), are typically affected. Osteoarthritis is the most common cause of a joint effusion of the knee.In smaller joints, such as at the fingers, hard bony enlargements, called Heberden's nodes (on the distal interphalangeal joints) or Bouchard's nodes (on the proximal interphalangeal joints), may form, and though they are not necessarily painful, they do limit the movement of the fingers significantly. Osteoarthritis of the toes may be a factor causing formation of bunions, rendering them red or swollen. Causes Damage from mechanical stress with insufficient self repair by joints is believed to be the primary cause of osteoarthritis. Sources of this stress may include misalignments of bones caused by congenital or pathogenic causes; mechanical injury; excess body weight; loss of strength in the muscles supporting a joint; and impairment of peripheral nerves, leading to sudden or uncoordinated movements. However exercise, including running in the absence of injury, has not been found to increase the risk of knee osteoarthritis. Nor has cracking one's knuckles been found to play a role. The risk of osteoarthritis increases with aging. Primary The development of osteoarthritis is correlated with a history of previous joint injury and with obesity, especially with respect to knees. Changes in sex hormone levels may play a role in the development of osteoarthritis, as it is more prevalent among post-menopausal women than among men of the same age. Conflicting evidence exists for the differences in hip and knee osteoarthritis in African Americans and Caucasians. Occupational Increased risk of developing knee and hip osteoarthritis was found among those who work with manual handling (e.g. lifting), have physically demanding work, walk at work, and have climbing tasks at work (e.g. climb stairs or ladders). With hip osteoarthritis, in particular, increased risk of development over time was found among those who work in bent or twisted positions. For knee osteoarthritis, in particular, increased risk was found among those who work in a kneeling or squatting position, experience heavy lifting in combination with a kneeling or squatting posture, and work standing up. Women and men have similar occupational risks for the development of osteoarthritis. Secondary This type of osteoarthritis is caused by other factors but the resulting pathology is the same as for primary osteoarthritis: Alkaptonuria Congenital disorders of joints Diabetes doubles the risk of having a joint replacement due to osteoarthritis and people with diabetes have joint replacements at a younger age than those without diabetes. Ehlers-Danlos syndrome Hemochromatosis and Wilson's disease Inflammatory diseases (such as Perthes' disease), (Lyme disease), and all chronic forms of arthritis (e.g., costochondritis, gout, and rheumatoid arthritis). In gout, uric acid crystals cause the cartilage to degenerate at a faster pace. Injury to joints or ligaments (such as the ACL) as a result of an accident or orthopedic operations. Ligamentous deterioration or instability may be a factor. Marfan syndrome Obesity Joint infectionPathophysiology While osteoarthritis is a degenerative joint disease that may cause gross cartilage loss and morphological damage to other joint tissues, more subtle biochemical changes occur in the earliest stages of osteoarthritis progression. The water content of healthy cartilage is finely balanced by compressive force driving water out and hydrostatic and osmotic pressure drawing water in. Collagen fibres exert .... Discover the Tw Harris popular books. 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Best Seller Tw Harris Books of 2024

  • Coffee Girl synopsis, comments

    Coffee Girl

    Sophie Sinclair

    Mackenzie "Kiki" Forbes finds herself in a pickle. Either become her snarky sister's nanny, or move halfway across the country to work as assistanttothestylist of a ...

  • The Odyssey synopsis, comments

    The Odyssey

    Homer

    An Apple Books Classic edition. Homer’s eighthcentury epic poem is a companion to The Iliad . It tells the story of Odysseus, who journeys by ship for 10 years after the Trojan War...

  • Silver Santa synopsis, comments

    Silver Santa

    Lacey Silks

    Trapped together on Christmas, their unintended onenight stand becomes a lifechanging encounter amidst the snow. Laura Young's professional role as a security guard at the Sil...

  • The Cupcake Cottage synopsis, comments

    The Cupcake Cottage

    Jean Oram

    NHL player Maverick Blades could fall in love with anyone... But he had to fall for a woman who falls under the Bro Code as untouchablehis best friend’s beautiful ex, DaisyMae Ray....

  • Caught Up with the Captain synopsis, comments

    Caught Up with the Captain

    Kait Nolan

    Can a retired naval commander and the love he left behind overcome a 34yearold secret to find their way to a second chance? Captain Mitchell Greyson is a man who believes in duty. ...

  • A Green Kind of Witch synopsis, comments

    A Green Kind of Witch

    Sierra Cross

    Cinderella crossed with Mean Girls.   That's what Hazel's daily existence feels like. Born to a family of elegant yet shallow Beige Witches, seventeen y...

  • All Fired Up synopsis, comments

    All Fired Up

    Kathryn Shay

    Captain Jarek Zenko, a war veteran and firefighter, meets Lacey Roth at a bar one night. They don’t share their real identities, even when they retreat to a hotel. When they meet t...

  • The Three Little Pigs synopsis, comments

    The Three Little Pigs

    Mark Lesky

    Classic fairy tales, legends and folk stories in short version without violence retold with lovely illustrations in simple language. Perfect for reading aloud to small chi...

  • Finding Cinderella synopsis, comments

    Finding Cinderella

    Colleen Hoover

    #1 New York Times bestselling author of It Starts with Us and It Ends With Us writes a free novella about the search for happily ever after. A chance encounter in the dark leads ei...

  • The Stoic Mind synopsis, comments

    The Stoic Mind

    Addy Osmani & GoLimitlesss

    Discover the timeless wisdom of Stoicism in a modern context with "The Stoic Mind," an enlightening visual guide by Addy Osmani and GoLimitlesss. This rich exploration co...

  • Noxious synopsis, comments

    Noxious

    Lexy Timms

    Stop setting yourself on fire to keep someone else warm. Brady and Levi have been together since high school, since before he became famous and started thinking only about himself....

  • Law of Attraction synopsis, comments

    Law of Attraction

    Jordan Hollis

    How to Finally Overcome the Hurdles of Manifesting Proven, effective and enjoyable ways to help you manifest faster… Right now, think of something that makes you successful. If you...

  • Pride and Prejudice synopsis, comments

    Pride and Prejudice

    Jane Austen

    An Apple Books Classic edition. Jane Austen’s beloved classic opens with this witty and very memorable line: “It is a truth universally acknowledged, that a single man in possessio...

  • Become A Better Version of Yourself synopsis, comments

    Become A Better Version of Yourself

    Ben Leighton

    This ebook contains golden nuggets on how to motivate, inspire and improve your current situation. It encompasses the holistic view of self improvement from mental& emotion...

  • Good Guy synopsis, comments

    Good Guy

    Kate Meader

    He's a Special Forces veteran making his pro hockey debut. She's a dogged sports reporter determined to get a scoop. She's also his best friend's widow . . . Fa...

  • Never Enough synopsis, comments

    Never Enough

    Lexy Timms

    Be good enough never is... Anthony Accardi is a man on a mission: make his father's watch company a success while bringing in millions of dollars. To do that, he needs an assi...

  • Death at Hazel House synopsis, comments

    Death at Hazel House

    Betty Rowlands

    ‘Riveting, can't put it down! I love this story… a wonderfully twisted tale of a crime that has more twists than I thought possible... fantastic.’ Goodreads Reviewer, 5 stars ...

  • Just Me synopsis, comments

    Just Me

    Lexy Timms

    We all need somewhere where we feel safe… After leaving her abusive husband, Katherine Marshall is out on her own for the first time. She's hopped from city to city to avoid t...

  • Teach Me synopsis, comments

    Teach Me

    Cassandra Dean

    From awardwinning author Cassandra Dean comes a tale where lessons of pleasure between a curious, sunshine widow and a dissolute, grumpy earl leads to passion and allconsuming love...

  • Masters of Restraint synopsis, comments

    Masters of Restraint

    Ines Johnson

    My new boss is good at giving orders. But his latest demand is NSFW. Especially when his two business partners want in on our deal. My new boss My boss’s boss Their investor &#...

  • Meditations synopsis, comments

    Meditations

    Emperor of Rome Marcus Aurelius

    Meditations is a series of personal writings by Marcus Aurelius, Roman Emperor 161–180 CE, setting forth his ideas on Stoic philosophy.

  • Nothing to Hide synopsis, comments

    Nothing to Hide

    Scarlett Finn

    Prize of a lifetime: travel the world with a celebrity billionaire. Come to LA with us, Roxie… It will be so much fun! We have tickets for a latenight talk show! What could possibl...

  • Christmas in Sweetbriar Cove synopsis, comments

    Christmas in Sweetbriar Cove

    Melody Grace

    Celebrate the holidays in Sweetbriar Cove with this festive romance collection, containing two sizzling smalltown holiday stories perfect for fans of Tessa Bailey, Sophie Kinsella...

  • Peace on Earth synopsis, comments

    Peace on Earth

    Maia Ross

    Crime never takes a holiday. Why should Irma? Irma Abercrombie is an energetic retiree with a shadowy past, a mean right hook, and a profound love of Christmas. Surrounded by seaso...

  • Dracula synopsis, comments

    Dracula

    Bram Stoker

    An Apple Books Classic edition. Few characters have seized readers’ imaginations quite like Count Dracula of Transylvania, the hero of Bram Stoker’s classic. The 1897 novel put vam...

  • How to Choose a Guy in 10 Days synopsis, comments

    How to Choose a Guy in 10 Days

    Lila Monroe

    The only thing more hilarious than the movies is… real life?! Fall in love with the sizzling grumpysunshine romantic comedy perfect for fans of Sophie Kinsella and Ali Hazlewood! ...

  • Awaken Me synopsis, comments

    Awaken Me

    Jenna Jacob

    He was more than a ghost haunting my dreams…he was real. By day, I’m Julianna Garrett …a prim, proper accountant. By night, I’m tormented by dreams of an alpha, ambereyed Adonis wh...

  • Alpha synopsis, comments

    Alpha

    Sybil Bartel

    Billionaire. Mercenary. Navy SEAL. The Teams trained me to be a killer. War taught me to be ruthless. Then an illfated mission proved I was human. Combat wounded, cut loose by the ...

  • The Seduction Series Boxset synopsis, comments

    The Seduction Series Boxset

    Roxy Sloane

    “Sensual, thrilling and wild!”   Discover the bestselling series in one collection: THE SEDUCTION, THE BARGAIN, and THE INVITATION. Perfect for fans of Ana Huang, Sierra S...

  • The Adventures of Sherlock Holmes synopsis, comments

    The Adventures of Sherlock Holmes

    Arthur Conan Doyle

    An Apple Books Classic You get not one, not two, but 25 gripping mysteries in Arthur Conan Doyle’s first of five collections of Sherlock Holmes short stories. Follow the brilliant ...

  • Once Upon A One-Night Stand synopsis, comments

    Once Upon A One-Night Stand

    Zoey Locke

    At first sight, there was electrifying chemistry.  So why not go for it? After all, Lynx Grove, the city's most eligible bachelor, wants to claim her, at least for th...

  • School of Potential synopsis, comments

    School of Potential

    W.J. May

    USA Today Bestselling author, W.J. May brings you a continuation of the international bestselling series, The Chronicles of Kerrigan! Come back and enjoy the famous characters, or ...

  • Salvation synopsis, comments

    Salvation

    Meghan O'Flynn

    If you like mouthy detectives, serial killers, and suspenseful mysteries that don't quit, this chilling and actionpacked hardboiled detective series has you covered! Try this ...

  • Whiskey Girl synopsis, comments

    Whiskey Girl

    Melissa Belle

    They'll do anything for each other…except commit. Logan Wild isn’t just the hottest broncriding cowboy in Texas. He’s also my best friendwith benefits. And that’s all we’ll ev...

  • Enemies With Benefits synopsis, comments

    Enemies With Benefits

    Roxie Noir

    I don’t love him. I don’t even like him. I just want him. Eli Loveless was my nemesis from the first day of kindergarten until we graduated high school. Everything I did, he had to...

  • Saltwater Cove synopsis, comments

    Saltwater Cove

    Amelia Addler

    Second chances...and the secrets that sabotage them. At 48 years old, Margie Clifton never expected to be starting her life all over again. But when her brother gifts her a propert...

  • Get Lucky synopsis, comments

    Get Lucky

    Lila Monroe

    Fall for the hot and hilarious romcom spin on 'The Hangover', perfect for fans of Tessa Bailey, Ali Hazelwood, and Emily Henry! What happens when you wake up in a hotel s...

  • Hard Love synopsis, comments

    Hard Love

    Peyton Banks

    He was football royalty. Legendary quarterback. A champion.  Reiner Strickland had led his team to three national championships and playing a knight in shining armor was a...

  • Man In The Water synopsis, comments

    Man In The Water

    Jon Hill

    An attempted murder. A missing spouse. And an international conspiracy that could change the world. Jack Green has always been skeptical of socalled facts. Though he's forced ...

  • The Count of Monte Cristo synopsis, comments

    The Count of Monte Cristo

    Alexandre Dumas

    An Apple Books Classic edition. Alexandre Dumas’ classic paints a portrait of Edmond Dantès, a dark and calculating man who is willing to wait years to exact his perfect plan for r...

  • The Next Girl synopsis, comments

    The Next Girl

    Carla Kovach

    IF YOU ONLY READ ONE BOOK THIS YEAR, MAKE IT THE NEXT GIRL... You thought he’d come to save you. You were wrong. ‘ Absolutely the best thriller I’ve read this year! ’ Goodreads Rev...

  • Holy Bible synopsis, comments

    Holy Bible

    The Church of Jesus Christ of Latter-day Saints

    The 2013 edition of the Holy Bible contains all of the study aids contained in the 1979 edition and includes revisions to the study aids, several new photos, updated maps, and adju...

  • Pretty Little Lies synopsis, comments

    Pretty Little Lies

    Ivy Thorn

    Four years ago, Nicolo Marchetti took my innocence. But he left me with something else Nicolo almost took everything from me. My virginity, my reputation, and very nearly my future...

  • His Own Heaven synopsis, comments

    His Own Heaven

    Jennie Kew

    Winner of the 2021 Passionate Plume Award for BDSM Romance Finalist in the 2021 Stiletto Contest for Contemporary Romance He taught her to trust, she taught him to love. ​ Lucy Bar...

  • The Honeymoon Homicide synopsis, comments

    The Honeymoon Homicide

    J. R. Mathis & Susan Mathis

    Enjoy this SmallTown Murder Mystery Featuring A Unique Sleuthing Couple I'm Father Tom Greer, a Catholic Priest in a smalltown parish who never expected this . . . When I came...

  • Teased by Fire synopsis, comments

    Teased by Fire

    Molly O'Hare

    From USA Today bestselling author Molly O’Hare comes an enemiestolovers, older brother’s best friend, romantic comedy with a curvy, antisocial, supernaturalobsessed, allyearround h...

  • Tempting the King synopsis, comments

    Tempting the King

    Jessa York

    An escaped Mafia Queen, hiding from her past. A Mafia King who wants to claim her… Giselle They think I'm lostbut I know better. I can never be found. The path I've creat...

  • The Holy Bible - King James Version synopsis, comments

    The Holy Bible - King James Version

    King James

    Holy Bible King James Version Few Sample Paragraphs from The Holy Bible eBook, Genesis (OT) 1 Gen. 1 IN the beginning God created the heaven and the earth. 2 And the earth was with...

  • Hot Off the Press synopsis, comments

    Hot Off the Press

    Lexy Timms

    "This is what really happened… reported by a free press, for a free people…" Wes Shaw leads a secret double life. As the secret owner of a billion dollar newspap...

  • A Christmas Carol synopsis, comments

    A Christmas Carol

    Charles Dickens

    An Apple Books Classic edition. It’s Christmas Eve in Victorian England. While some families don’t know where their next meal will come from, Ebenezer Scrooge sits in his large hom...