Y Liu Popular Books
Y Liu Biography & Facts
David Ruchien Liu (born 1973) is an American molecular biologist and chemist. He is the Richard Merkin Professor, Director of the Merkin Institute of Transformative Technologies in Healthcare, and Vice-Chair of the Faculty at the Broad Institute of Harvard and MIT; Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry and Chemical Biology at Harvard University; and Howard Hughes Medical Institute Investigator. Early life and education Liu was born in Riverside, California on June 12, 1973. Both his parents immigrated to the United States from Taiwan. His father is an aerospace engineer; his mother is a retired physics professor at the University of California, Riverside. While in high school, Liu finished second in the 1990 national Westinghouse Science Talent Search. He received his Bachelor of Arts in chemistry from Harvard University in 1994, graduating summa cum laude and first in his class. While an undergraduate, he worked in the synthetic chemistry laboratory of Nobel Laureate E.J. Corey. Liu received his Ph.D. in organic chemistry from the University of California, Berkeley in 1999, supervised by Peter G. Schultz. Academic career Liu graduated first in his class at Harvard in 1994. He performed organic and bioorganic chemistry research on sterol biosynthesis under Professor E.J. Corey's guidance as an undergraduate. During his Ph.D. research with Professor Peter Schultz at Berkeley, Liu initiated the first general effort to expand the genetic code in living cells. He earned his Ph.D. in 1999 and became assistant professor of chemistry and chemical biology at Harvard in the same year. He was promoted to associate professor in 2003 and to full professor in 2005. Liu became a Howard Hughes Medical Investigator in 2005 and joined the JASONs, academic science advisors to the U.S. government, in 2009. He was honored as a Harvard College Professor in 2007, in part for his undergraduate teaching. His introductory life sciences course, beginning in 2005, became Harvard's largest natural sciences course. Liu has earned several university-wide distinctions for teaching at Harvard, including the Joseph R. Levenson Memorial Teaching Prize, the Roslyn Abramson Award, and a Harvard College Professorship. Liu has published more than 225 papers and is the inventor of more than 90 issued U.S. patents. His research accomplishments have earned distinctions including the Ronald Breslow Award for Biomimetic Chemistry, the American Chemical Society Pure Chemistry Award, the Arthur C. Cope Young Scholar Award, and awards from the Sloan Foundation, Beckman Foundation, NSF CAREER Program, and Searle Scholars Program. In 2016, he was named one of the Top 20 Translational Researchers in the world by Nature Biotechnology, and in 2017 and 2019 was named to the Nature’s 10 researchers in world and to the Foreign Policy Leading Global Thinkers. In April 2019, Liu delivered a TED talk on base editing in Vancouver at TED2019, resulting in a standing ovation from the live audience. In 2019, prime editing was named as one of Nature's 10 remarkable papers from 2019 and one of The Scientist's top technical advances. In 2020, Liu earned the American Chemical Society David Perlman Award and the American Chemical Society ACS Chemical Biology Lectureship Award, was elected to the National Academy of Science (NAS), the National Academy of Medicine (NAM) and was named as a Fellow of the American Association for the Advancement of Science (AAAS). In 2022, he was awarded the King Faisal Prize in Medicine. Research Liu's research group pioneered base editing, a new method of genome editing that enables the direct and precise conversion of a single base to another base in the genome of living cells, without making DNA double-stranded breaks (DSBs) that lead to complex mixtures of insertions, deletions, and DNA rearrangements. Liu's research group also pioneered prime editing, a versatile genome editing method that can install all possible base-to-base conversions, insertions, deletions, and combinations in mammalian cells without requiring double-strand DNA breaks or donor DNA templates. DNA-Templated Synthesis (DTS) generated some of the first examples of DNA-encoded libraries (DELs), now commonly used in drug discovery efforts in academia and in pharmaceutical companies. His lab also developed phage-assisted continuous evolution (PACE), a technique that uses the short 10-minute lifespan of M13 bacteriophage to achieve the rapid evolution of useful proteins. The lab has used PACE and its directed evolution efforts to generate new genome editing tools that allow for expanded DNA accessibility and DNA base conversions. He has published over 230 peer-reviewed publications and his H-index is ≥130 according to Google Scholar. Commercial activity Liu co-founded Editas Medicine (genome editing with CRISPR nucleases for human therapeutics), Pairwise Plants (genome editing for agriculture), Beam Therapeutics (base editing for human therapeutics), Exo Therapeutics (novel small-molecule drug discovery), Chroma Medicine (genomic medicines that harness epigenetics), Resonance Medicine (novel enzymatic solutions for unment challenges in medicine), and Nvelop Therapeutics (novel gene editing delivery technologies). He is the scientific founder of Prime Medicine (prime editing for human therapeutics). Liu also founded Permeon Biologics and Ensemble Therapeutics. Permeon Biologics was founded in 2011 by Liu and Flagship Ventures to develop a class of proteins to enable the transport of large molecules such as antibodies into cells to facilitate development of "intrabody" therapeutics and ceased its operations in 2015. Ensemble Therapeutics was founded in 2004 with funding from Flagship Ventures to develop Liu's work on macrocycles; the company raised about $40M and struck several pharmaceutical partnerships, but was shut down in 2017 before any of its lead compounds had reached the market. Personal life He met his wife, Julie Liu, while attending U.C Berkeley. Selected papers Gartner, ZJ; Liu, DR (July 2001). "The generality of DNA-templated synthesis as a basis for evolving non-natural small molecules". J. Am. Chem. Soc. 123 (28): 6961–3. doi:10.1021/ja015873n. PMC 2820563. PMID 11448217. Kanan, MW; Rozenman, MM; Sakurai, K; Snyder, TM; Liu, DR (2004). "Reaction discovery enabled by DNA-templated synthesis and in vitro selection". Nature. 431 (7008): 545–9. Bibcode:2004Natur.431..545K. doi:10.1038/nature02920. PMC 2814052. PMID 15457254. Gartner, ZJ; Tse, BN; Grubina, R; Doyon, JB; Snyder, TM; Liu, DR (September 2004). "DNA-templated organic synthesis and selection of a library of macrocycles". Science. 305 (5690): 1601–5. Bibcode:2004Sci...305.1601G. doi:10.1126/science.1102629. PMC 2814051. PMID 15319493. Georghiou, G; Kleiner, RE; Pulkoski-Gross, M; Liu, DR; Seeliger, MA (2012). "Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles". Nature Chemica.... Discover the Y Liu popular books. Find the top 100 most popular Y Liu books.
Best Seller Y Liu Books of 2024
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The Order of the Pure Moon Reflected in Water
Zen ChoA 2021 Locus Award Finalist!A Lambda Literary Award FinalistA Book Riot MustRead Fantasy of 2020Amazon's Best of 2020 So Far“Fantastic, defiant, utterly brilliant.” Ken LiuZen Cho ...
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Ecclesiastical History of the English People
BEDE, Leo Sherley-Price & D. H. FarmerWritten in AD 731, Bede's work opens with a background sketch of Roman Britain's geography and history. It goes on to tell of the kings and bishops, monks and nuns who helped to de...
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Sherlock Holmes and the Sussex Sea-Devils
James LovegroveThe stunning new novel from the New York Times bestselling author of The Age of Odin, in which the worlds of Arthur Conan Doyle and H.P. Lovecraft collide.It is the autumn of 1910,...
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The Veiled Throne
Ken LiuWith the invasion of Dara complete, and the Wall of Storms breached, the world has opened to new possibilities for the gods and peoples of both empires as the sweeping saga of the ...
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Speaking Bones
Ken LiuThe battle continues in this silkpunk fantasy as science and destiny collide against the will of the gods in this final installment in the epic Dandelion Dynasty series from the “g...
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The Further Adventures of Sherlock Holmes - The Haunting of Torre Abbey
Carole BuggeA HAUNTED HOUSESherlock Holmes receives a request for aid from Lord Cary, whose family home, Torre Abbey, is seemingly haunted. While skeptical, Holmes believes that the Carys are ...
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Sherlock Holmes - Masters of Lies
Philip Purser-HallardA brandnew, brilliantly twisty Sherlock Holmes mystery from 'best kept secret of British genre writing' British Fantasy Society When investigating what seems to be a su...
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Robots vs. Fairies
Dominik Parisien & Navah WolfeFeatured in the Netflix series Love, Death & RobotsA unique anthology of allnew stories that challenges authors to throw down the gauntlet in an epic genre battle and demands a...
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Sherlock Holmes - The Red Tower
Mark A. LathamThe brand new adventure from the author of A Betrayal in Blood, in which Sherlock Holmes and Dr Watson are faced with a fiendish locked room mystery.Dr Watson has been invited to C...
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Rent a Boyfriend
Gloria ChaoTo All the Boys I’ve Loved Before meets The Farewell in this “entertaining and nuanced” (Kirkus Reviews) romantic comedy about a college student who hires a fake boyfriend to appea...
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The Further Adventures of Sherlock Holmes - The Instrument of Death
David Stuart DaviesA brandnew Sherlock Holmes mystery from acclaimed Sherlockian author David Stuart Davies, featuring the sinister Dr CaligariSherlock Holmes has just uncovered the truth about the t...
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The Wall of Storms
Ken LiuOne of the Time 100 Best Fantasy Books Of All TimeIn the muchanticipated sequel to the “magnificent fantasy epic” (NPR) Grace of Kings, Emperor Kuni Garu is faced with the invasion...
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The Brightest Star
Gail TsukiyamaA LIBRARYREADS PICK AND BEST BOOK CLUB PICK OF 2023 “A writer of astonishing grace, delicacy, and feeling.”Michael Chabon, Pulitzer Prizewinning author of The Amazing Adventures of...
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The Wandering Earth
Cixin Liu, Christophe Bec, Stefano Raffaele & S. Qiouyi LuThe second in a new series of graphic novels from Hugo Awardwinning author Liu Cixin and Talos Press The lifebringing sun is on track to have a catastrophic helium flash within the...
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Supernova Era
Cixin Liu & Joel MartinsenFrom science fiction legend Cixin Liu, the New York Times bestselling and awardwinning author of The ThreeBody Problem, comes a vision of the future that reads “like Ursula K Le Gu...
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The Accidental Asian
Eric LiuBeyond black and white, native and alien, lies a vast and fertile field of human experience. It is here that Eric Liu, former speechwriter for President Clinton and noted political...
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Sherlock Holmes and the Beast of the Stapletons
James LovegroveNew York Times bestselling author James Lovegrove's continues the story of Sherlock Holmes and The Hound of the Baskervilles, as five years later, another monstrous creature stalks...
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The Book of Swords
Gardner Dozois, George R.R. Martin, Robin Hobb, Scott Lynch & Garth NixNew epic fantasy in the grand traditionincluding a neverbeforepublished Song of Ice and Fire story by George R. R. Martin! Fantasy fiction has produced some of the most unforgettab...
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Master Assassins
Robert V.S. Redick2018 BookNest Fantasy Awards Finalist for Best Novel “This book has everything I love: Clean, crisp worldbuilding. Characters that live and breathe. A story that teases and surpris...
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The Stars Turned Inside Out
Nova Jacobs“Many and wondrous are the charms of this witty, suspenseful, and enchanting book.” The Wall Street Journal The discovery of a suspicious death at a famous Swiss physics laboratory...
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Silent Spring
Rachel CarsonTHE CLASSIC THAT LAUNCHED THE ENVIRONMENTAL MOVEMENTFEATURED ON NETFLIX'S 3 BODY PROBLEM“Rachel Carson is a pivotal figure of the twentieth century…people who thought one way befor...
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One True Loves
Taylor Jenkins ReidNow a major film! Author of the New York Times bestselling author of The Seven Husbands of Evelyn Hugo Named a Best Book of Summer by Cosmopolitan InStyle Redbook Us Weekly P...
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Sherlock Holmes and the Miskatonic Monstrosities
James LovegroveIt is the spring of 1895, and more than a decade of combating eldritch entities has cost Dr John Watson his beloved wife Mary, and nearly broken the health of Sherlock Holmes....
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The Dead Can Wait
Robert RyanDeep in England's green and pleasant land something evil lurks… Dr John Watson, Sherlock Holmes' stalwart companion, is back home, fresh from his time in the trenches of Flanders F...
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The Further Adventures of Sherlock Holmes - Revenge from the Grave
David Stuart DaviesA brandnew Sherlock Holmes mystery from acclaimed Sherlockian author David Stuart Davies, featuring the return of the sinister Moriarty gang...When Professor James Moriarty plunged...
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Sobre hormigas y dinosaurios
Cixin LiuEl autor de El problema de los tres cuerpos regresa a la ciencia ficción con una advertencia ecológica en forma de fábula: la historia de unos pobres dinosaurios que no escucharon ...
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Black Wolves
Kate ElliottAn exiled captain returns to help the son of the king who died under his protection in this rich and multilayered first book in an actionpacked new series. Twenty two years have pa...
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Mastering the Art of War
Liang Zhuge, Liu Ji & Thomas ClearyTwo master strategists delve into the essential priciples of Sun Tzu's The Art of War, revealing what they teach us about leadership, success, and moreComposed by two pro...
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The Liu Seong Kuntao Broken Mirror System
Reginald McKissickThis book provides an overview of the martial art system derived from Willem Reeders (19171990) and his uncle Liu Seong. The hybrid system inherited much from Liu Seong since he wa...
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Mycroft and Sherlock
Kareem Abdul-Jabbar & Anna WaterhouseThe new novel by NBA AllStar Kareem AbdulJabbar, starring brothers Mycroft and Sherlock Holmes.It is 1872, and a series of gruesome murders is the talk of London. Mycroft Holmesnow...
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A Study in Murder
Robert RyanA stunning Dr Watson thriller perfect for all fans of Sherlock.The year is 1917 and Doctor John Watson is held in a notorious POW camp deep in enemy Germany, there as Medical Offic...
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The Manifestations of Sherlock Holmes
James LovegroveTwelve sensational Sherlock Holmes short stories from a bestselling master of the genre.Maverick detective Sherlock Holmes and his faithful chronicler Dr John Watson return in twel...
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Press Start to Play
Daniel H. Wilson & John Joseph AdamsIT’S DANGEROUS TO GO ALONE! TAKE THIS. You are standing in a room filled with books, faced with a difficult decision. Suddenly, one with a distinctive cover catches your ...
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Sea of Dreams
Cixin Liu & Rodolfo SantulloThe first in a new series of graphic novels from Hugo Awardwinning author Liu Cixin and Talos Press An annual ice sculpture festival draws the attention of an extraterrestrial visi...
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The Rig
Roger LevyOn a desert planet, two boys meet, sparking a friendship that will change human society forever. On the windswept world of Bleak, a string of murders lead a writer to a story with ...
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Within the Flames
Marjorie Liu“Marjorie Liu is magic! Her writing is passionate, lyric, gritty, and riveting. She belongs high on everyone’s mustread list.”Elizabeth Lowell“Anyone who loves my work should love ...
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The Starlit Wood
Dominik Parisien & Navah WolfeThis “first rate anthology of reimagined fairy tales” (Locus Magazine) features an allstar lineup of awardwinning and critically acclaimed writers.Once upon a time. It’s how so man...