Osmosis Jones Popular Books

Osmosis Jones Biography & Facts

Osmosis Jones is a 2001 American live-action/animated action comedy film written by Marc Hyman. Combining live-action sequences directed by the Farrelly brothers and animation directed by Piet Kroon and Tom Sito, the film stars the voices of Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, and William Shatner alongside Molly Shannon, Chris Elliott, and Bill Murray in live-action roles. It follows the title character, an anthropomorphic white blood cell, as he teams up with a cold pill to protect his unhealthy human host from a villainous, highly contagious virus called "the Red Death". The film premiered on August 7, 2001, and was released theatrically three days later. It received mixed reviews from critics, who praised the world building, the animation, story, and voice performances, but criticized the inconsistent tone of the live-action portions and overuse of gross-out humor. The film was also a box-office failure, grossing $14 million worldwide against a $70 million budget. Despite the poor financial response, in 2002 the film was followed by the animated television series Ozzy & Drix, which aired on Kids' WB to 2004. Plot Frank DeTorre is an unhealthy zookeeper widower at Sucat Memorial Zoo in Rhode Island. He copes with the death of his wife Maggie by overeating unhealthy foods and foregoing basic hygiene, much to his daughter Shane's embarrassment. Inside his body, called the "City of Frank" by its anthropomorphic inhabitants, white blood cell Osmosis "Ozzy" Jones is a quick-witted officer of the Frank Police Department whose attempts to catch germs end up causing trouble in Frank's body. One day, desperate to be re-elected, the corrupt Mayor Phlegmming doubles down on his junk food policies, ignoring their effect on Frank's health. This induces Frank to eat a boiled egg that had fallen into a chimpanzee's habitat, allowing Thrax, a virus known as "La Muerte Roja" ("The Red Death"), to enter his body. To placate his secretary Leah Estrogen, Phlegmming instructs Frank to take a cold pill, Special Agent Drixenol "Drix" Drixobenzometaphedramine, who disinfects the throat but unknowingly covers up evidence of Thrax's arrival. Ozzy is ordered to assist Drix's investigation while Thrax takes over a gang of sweat germs run by local crime boss Scabies. Thrax and his gang attack the dam in Frank's nose, nearly killing Drix before Ozzy saves him. Ozzy and Drix get into an argument, but after Ozzy reveals Thrax and his gang as the cause of the mucus dam breakage, Drix sticks with Ozzy. Ozzy tells Drix the reason for his poor reputation: two years ago at a school science fair, Ozzy induced Frank to vomit a contaminated oyster onto Shane's science and physical education teacher, Mrs. Boyd; this caused Frank to be fired from his previous job at the local pea soup factory and be banned from visiting Shane's school, and Ozzy had been suspended and then demoted to patrol duty in the mouth for his role in the public humiliation. Drix agrees with Ozzy that he did the right thing, and the duo pay a visit to Ozzy's flu vaccine informant, Chill, who directs them to Thrax's hideout – a germ-ridden nightclub in a large zit on Frank's forehead. Ozzy goes undercover and infiltrates the gang, learning that Thrax, wanting to be known as the most dangerous virus in medical history, intends to masquerade as a common cold and use his knowledge of DNA to kill Frank within a record forty-eight hours. When Ozzy is discovered, Drix comes to his aid, causing a brawl which culminates in the zit being popped by a grenade. Its pus lands on Mrs. Boyd's lip during a conversation with Frank, foiling his chance to apologize. Furious, Phlegmming closes the investigation, dismisses Ozzy from the police force and orders Drix to leave the body after reminding him that his services are only temporary. Having survived the zit's destruction, Thrax attacks the hypothalamus, stealing a crucial nucleotide before abducting Leah and preparing to flee via the mouth. His actions cause Frank to faint and develop a high fever, prompting his brother, Bob, to take him to the hospital, to Phlegmming's dismay. Having discovered Thrax's survival, Ozzy convinces Drix to stay. They intercept Thrax in the uvula and save Leah, but Thrax uses pollen to induce Frank to sneeze him out of the mouth. Drix launches Ozzy after him and they land on Shane's cornea. As they fight, falling onto one of Shane's false eyelashes, Ozzy tricks Thrax into trapping his hand in the lash and escapes as the lash falls into a beaker of alcohol, dissolving Thrax. As Frank's temperature surpasses 108 °F (42 °C), he goes into cardiac arrest. Riding one of Shane's tears back to Frank's body as she mourns him, Ozzy returns with the stolen nucleotide, reviving Frank just in time. As Ozzy is hailed a hero and welcomed back into the police force, Drix is allowed to stay as his new partner and Ozzy enters a relationship with Leah. Having narrowly cheated death, Frank commits to a healthier lifestyle, leading Phlegmming to lose the election in a landslide to his opponent, Tom Colonic. Reduced to janitorial duty in the bowels, Phlegmming foolishly ignores a notice not to push a button that triggers Frank's flatulence, resulting in his ejection from the body. Cast Chris Rock as Osmosis "Ozzy" Jones, a quick-witted white blood cell with an impulsive personality. Bill Murray as Francis "Frank" DeTorre, Shane's widowed father and Bob's brother, in whom Ozzy and his friends live. Laurence Fishburne as Thrax, a villainous and deadly virus. David Hyde Pierce as Special Agent Drixenol "Drix" Drixobenzometaphedramine, a by-the-book cold pill who becomes Ozzy's best friend and partner. Brandy Norwood as Leah Estrogen, Mayor Phlegmming's secretary and Ozzy's love interest. William Shatner as Mayor Phlegmming, the arrogant, incompetent and corrupt mayor of the City of Frank. Molly Shannon as Mrs. Boyd, Shane's science and P.E. teacher. Chris Elliott as Robert "Bob" DeTorre, Frank's brother and Shane's uncle. Elena Franklin as Shane DeTorre, Frank's 10-year-old daughter and Bob's niece. Ron Howard as Tom Colonic, Phlegmming's rival for the mayoralty of the City of Frank. Twisted Brown Trucker members Kid Rock, Kenny Olsen, Jason Krause, Joe C., Stefanie Eulinberg, Jimmie "Bones" Trombly, and Uncle Kracker provide the voices of the fictional band "Kidney Rock". Joel Silver makes an uncredited appearance as the police chief. Additional voices are provided by Jonathan Adams, Carlos Alazraqui, Eddie Barth, Rodger Bumpass, Paul Christie, Antonio Fargas, Eddie Frierson, Donald Fullilove, Jackie Gonneau, Richard Steven Horvitz, Rif Hutton, Joyce Kurtz, Anne Lockhart, Sherry Lynn, Danny Mann, Mickie McGowan, "Stuttering" John Melendez, Paul Pape, Chris Phillips, Al Rodrigo, Herschel Sparber, Doug Stone, Steve Susskind, and Robert Wisdom. Production Osmosis Jones went through development hell during production. The animated sequences, directed by To.... Discover the Osmosis Jones popular books. Find the top 100 most popular Osmosis Jones books.